{"id":13366,"date":"2021-05-13T18:38:32","date_gmt":"2021-05-13T22:38:32","guid":{"rendered":"https:\/\/clone.arsacs.com\/?page_id=13366"},"modified":"2026-04-10T12:24:04","modified_gmt":"2026-04-10T16:24:04","slug":"news","status":"publish","type":"page","link":"https:\/\/2026.arsacs.com\/fr\/news\/","title":{"rendered":"News"},"content":{"rendered":"
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\"Running<\/span><\/a><\/div>

Running in support of families affected by ARSACS<\/a><\/h2>

Avr 8, 2026<\/span><\/p>

On November 1, 2024, Christos Scarpinato lost his mother to Autosomal Recessive Spastic Ataxia of Charlevoix\u2013Saguenay (ARSACS), a rare and degenerative neurological disease. Two years later, he is taking on a meaningful challenge: running a marathon in her memory and…<\/p>\n<\/div>read more…<\/a><\/div><\/article>

Dimethyl Fumarate Tested in an ARSACS Mouse Model<\/a><\/h2>

Mar 31, 2026<\/span><\/p>

Consult the research report by Drs. Justin Wolters and Huaxia Wang on their study of dimethyl fumarate in the ARSACS mouse model. This work was made possible through the financial support of the Ataxia Charlevoix-Saguenay Foundation. Read the report here.<\/p>\n<\/div>read more…<\/a><\/div><\/article>

\"Infolettre<\/span><\/a><\/div>

Infolettre #6 \u00c9dition Hiver 2026<\/a><\/h2>

Mar 12, 2026<\/span><\/p>

Dans cette \u00e9dition, nous mettons en lumi\u00e8re deux rapports scientifiques r\u00e9cemment publi\u00e9s sur l\u2019ARSACS. Nous annon\u00e7ons \u00e9galement notre appel d\u2019offres pour les projets de recherche 2026 et partageons des informations sur notre prochain symposium \u00e0 Atlanta (\u00c9tats-Unis)….<\/p>\n<\/div>read more…<\/a><\/div><\/article>

\"Newsletter<\/span><\/a><\/div>

Infolettre #6 \u00c9dition Hiver 2026<\/a><\/h2>

Mar 12, 2026<\/span><\/p>

We are excited to share the latest news from the Ataxia Charlevoix\u2013Saguenay Foundation. In this edition, we highlight 2 published scientific reports on ARSACS. We announce our 2026 Research Grants Call for Proposals, and share details about our upcoming Symposium in…<\/p>\n<\/div>read more…<\/a><\/div><\/article>

\"8e<\/span><\/a><\/div>

8e \u00e9dition du Symposium ARSACS<\/a><\/h2>

Mar 5, 2026<\/span><\/p>

Nous sommes heureux d\u2019annoncer la 8e \u00e9dition du Symposium ARSACS, qui se tiendra le 9 novembre 2026, \u00e0 titre de r\u00e9union satellite officielle du Congr\u00e8s international sur la recherche sur les ataxies (ICAR) \u00e0 Atlanta. Ce symposium en pr\u00e9sentiel r\u00e9unira des chercheurs…<\/p>\n<\/div>read more…<\/a><\/div><\/article>

\"8th<\/span><\/a><\/div>

8th edition of the ARSACS Symposium<\/a><\/h2>

Mar 5, 2026<\/span><\/p>

We are pleased to announce the 8th edition of the ARSACS Symposium, to be held on November 9, 2026, as an official satellite meeting of the International Congress for Ataxia Research (ICAR) in Atlanta. This in-person event will bring together leading researchers and…<\/p>\n<\/div>read more…<\/a><\/div><\/article><\/div><\/div><\/div>\n<\/div>\n<\/div>\n\n

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\"Une<\/span><\/a><\/div>

Une voie vers de nouvelles strat\u00e9gies de traitement de l\u2019ARSACS<\/a><\/h2>

F\u00e9v 23, 2026<\/span><\/p>

Lisez le r\u00e9cent rapport de Stefan Strack sur l’ARSACS, notamment ses travaux r\u00e9ussis sur l’administration du g\u00e8ne Sacsin humain complet en th\u00e9rapie g\u00e9nique. Lire l’article (disponible en anglais seulement).<\/p>\n<\/div><\/div><\/article>

\"Developing<\/span><\/a><\/div>

Developing new approaches to treating ARSACS<\/a><\/h2>

F\u00e9v 23, 2026<\/span><\/p>

Read all about Stefan Strack\u2019s recent report on ARSACS, especially with his work successfully delivering the full-length humain Sacsin in gene therapy. Read the article<\/p>\n<\/div><\/div><\/article>

Appel d’offres 2026 – Financement de la recherche<\/a><\/h2>

F\u00e9v 19, 2026<\/span><\/p>

Pour plus d’information:Appel d’offre – Financement Soumettre une demande 2026<\/p>\n<\/div><\/div><\/article>

\"2026<\/span><\/a><\/div>

2026 Research Grants Call for Proposals<\/a><\/h2>

F\u00e9v 19, 2026<\/span><\/p>

For more information :Call for Proposal To apply: Application Form<\/p>\n<\/div><\/div><\/article>

Developing conditional mouse models and new approaches to treating ARSACS \u2013 by Dr. Stefan Strack, University of Iowa Carver College of Medicine<\/a><\/h2>

F\u00e9v 1, 2026<\/span><\/p>

Developing conditional mouse models and new approaches to treating ARSACS \u2013 by Dr. Stefan Strack, University of Iowa Carver College of Medicine . This project was funded by the ARSACS Foundation in 2024\u20132025<\/p>\n<\/div><\/div><\/article>

\"D\u00e9couvrez<\/span><\/a><\/div>

D\u00e9couvrez le plus r\u00e9cent article des Dres Watt et McKinney<\/a><\/h2>

Jan 13, 2026<\/span><\/p>

“Alterations in the Na+\/H+ Exchanger NHE6 and Glutamate Transporters may Influence Purkinje Cell Fate in ARSACS”- article publi\u00e9 dans le Cerebellum Journal en 2025. Consultez le rapport complet ici<\/p>\n<\/div><\/div><\/article>

\"Discover<\/span><\/a><\/div>

Discover the latest article from Drs. Watt & McKinney<\/a><\/h2>

Jan 13, 2026<\/span><\/p>

“Alterations in the Na+\/H+ Exchanger NHE6 and Glutamate Transporters may Influence Purkinje Cell Fate in ARSACS” article published recently in the Cerebellum journal. Read the full report here<\/p>\n<\/div><\/div><\/article>

Towards glial-targeted therapies of ARSACS \u2013 by Drs Herrera\/Fernandes\/Adams, University of Lisbon \/ Bilkent University<\/a><\/h2>

Jan 8, 2026<\/span><\/p>

Towards glial-targeted therapies of ARSACS \u2013 by Drs Herrera\/Fernandes\/Adams, University of Lisbon \/ Bilkent University . This project was funded by the ARSACS Foundation in 2022-2023<\/p>\n<\/div><\/div><\/article>

Retinal pigment epithelium (RPE) cell system to uncover the molecular mechanisms of ARSACS-related retinal defects \u2013 by Dr. Daniele Galatolo, IRCCS Fondazione Stella Maris, Pisa, Italy<\/a><\/h2>

Jan 8, 2026<\/span><\/p>

Retinal pigment epithelium (RPE) cell system to uncover the molecular mechanisms of ARSACS-related retinal defects \u2013 by Dr. Daniele Galatolo, IRCCS Fondazione Stella Maris, Pisa, Italy . This project was funded by the ARSACS Foundation in 2022-2023<\/p>\n<\/div><\/div><\/article>

Understanding the role of Metals in ARSACS \u2013 by Dr. Graham George, University of Saskatchewan<\/a><\/h2>

Jan 8, 2026<\/span><\/p>

Understanding the role of Metals in ARSACS \u2013 by Dr. Graham George, University of Saskatchewan funded jointly by the Foundation and the Richardson Research Fund in 2020-2021<\/p>\n<\/div><\/div><\/article>

\"1.4<\/span><\/a><\/div>

1.4 millions raised for research<\/a><\/h2>

Jan 8, 2026<\/span><\/p>

On November 27,2025 the 18th edition of the D\u00eener des Producteurs took place. The evening was a true success, with nearly $1.4 million raised in support of research. A special thank-you to our guest chef and winemaker: Chef Julien Royer of Odette in Singapore, as well…<\/p>\n<\/div><\/div><\/article>

\"1,4<\/span><\/a><\/div>

1,4 M$ amass\u00e9s pour la recherche<\/a><\/h2>

Jan 8, 2026<\/span><\/p>

Le 27 novembre dernier a eu lieu la 18e \u00e9dition du D\u00eener des Producteurs. La soir\u00e9e a connu un v\u00e9ritable succ\u00e8s et pr\u00e8s de 1,4 million de dollars ont \u00e9t\u00e9 amass\u00e9s au profit de la recherche. Un merci tout particulier \u00e0 notre chef et vigneron invit\u00e9s : le chef Julien…<\/p>\n<\/div><\/div><\/article>

\"World<\/span><\/a><\/div>

World Orphan Drug Congress\u00a02025<\/a><\/h2>

Jan 5, 2026<\/span><\/p>

En novembre dernier, l\u2019Ataxie Charlevoix-Saguenay a brillamment \u00e9t\u00e9 repr\u00e9sent\u00e9e au\u00a0World Orphan Drug Congress\u00a0\u00e0 Amsterdam. En tant que conf\u00e9renciers, les Drs Francesca Maltecca, Daniele De Ritis, Bart van de Warrenburg et Sonia Gobeil ont partag\u00e9 leur expertise et…<\/p>\n<\/div><\/div><\/article>

\"World<\/span><\/a><\/div>

World Orphan Drug Congress 2025<\/a><\/h2>

Jan 5, 2026<\/span><\/p>

Last November, Charlevoix\u2013Saguenay Ataxia Foundation was brilliantly represented at the World Orphan Drug Congress in Amsterdam. As speakers, Drs. Francesca Maltecca, Daniele De Ritis, Bart van de Warrentburg, and Sonia Gobeil shared their expertise and unwavering…<\/p>\n<\/div><\/div><\/article>

Alterations in the Na+\/H+Exchanger NHE6 and Glutamate Transportersmay Influence Purkinje Cell Fate in ARSACS<\/a><\/h2>

Jan 1, 2026<\/span><\/p>

Alterations in the Na+\/H+Exchanger NHE6 and Glutamate Transportersmay Influence Purkinje Cell Fate in ARSACS \u2013 Louis-Charles Masson, Atchaya S. Kanagasabai, Brenda Toscano M\u00e1rquez, Julia Tourbina-Kolomiets, Francois Charron, Alanna J. Watt, R. Anne McKinney. Research…<\/p>\n<\/div><\/div><\/article>

\"A<\/span><\/a><\/div>

A city united behind the ARSACS cause<\/a><\/h2>

Jan 1, 2026<\/span><\/p>

We would like to acknowledge the tremendous participation of the Anse Saint – Jean residents at the benefit bingo organized to support the research for children with ARSACS. As a result of their generosity, $13000 was raised. Thank you to everyone who attended, the…<\/p>\n<\/div><\/div><\/article>

\"Une<\/span><\/a><\/div>

Une ville unie pour la cause ARSACS<\/a><\/h2>

Jan 1, 2026<\/span><\/p>

Nous souhaitons souligner la formidable mobilisation des gens de l’Anse Saint- Jean lors du bingo b\u00e9n\u00e9fice organis\u00e9 au profit de la recherche afin d’aider les enfants atteints de l’ARSACS. Gr\u00e2ce \u00e0 leur g\u00e9n\u00e9rosit\u00e9, un montant de 1 300$ a \u00e9t\u00e9 amass\u00e9. Merci \u00e0 toutes les…<\/p>\n<\/div><\/div><\/article>

\"La<\/span><\/a><\/div>

La th\u00e9rapie g\u00e9nique pour l\u2019ARSACS : des \u00e9tudes en cours<\/a><\/h2>

D\u00e9c 10, 2025<\/span><\/p>

Les avanc\u00e9es des \u00e9tudes pr\u00e9cliniques sont prometteuses pour le d\u00e9veloppement d\u2019une th\u00e9rapie g\u00e9nique pour l\u2019ARSACS, et des tests d\u2019efficacit\u00e9 chez des souris symptomatiques sont en cours. Pour en savoir plus sur ce projet de recherche en cours, cliquez ici.<\/p>\n<\/div><\/div><\/article>

\"Gene<\/span><\/a><\/div>

Gene therapy for ARSACS: preclinical studies underway<\/a><\/h2>

D\u00e9c 10, 2025<\/span><\/p>

The advances in preclinical studies are promising for the development of a gene therapy for ARSACS and efficacy in symptomatic mice are in progress. To know more about this ongoing research project, click here<\/p>\n<\/div><\/div><\/article>

\"Virtual<\/span><\/a><\/div>

Virtual Auction is Back!<\/a><\/h2>

Nov 17, 2025<\/span><\/p>

As part of the Diner des Producteurs 2025, an ideal opportunity to find exceptional lots while supporting ARSACS research. New this year: you can make a donation to fund directly a clinical trial for the Charlevoix Saguenay Ataxia. Every gesture counts – Don’t miss…<\/p>\n<\/div><\/div><\/article>

\"L\u2019encan<\/span><\/a><\/div>

L\u2019encan virtuel est de retour !<\/a><\/h2>

Nov 17, 2025<\/span><\/p>

Une occasion id\u00e9ale dans le cadre du Diner des Producteurs 2025 de d\u00e9nicher des lots exceptionnels tout en soutenant la recherche. \u00a0Nouveaut\u00e9 cette ann\u00e9e\u00a0: vous pouvez faire un don directement pour financer un essai clinique pour l’ataxie Charlevoix- Saguenay. Chaque…<\/p>\n<\/div><\/div><\/article>

\"Le<\/span><\/a><\/div>

Le “Charity Ball” – Un grand succ\u00e8s!<\/a><\/h2>

Nov 13, 2025<\/span><\/p>

Le premier “Charity Ball” organis\u00e9 par Maxine Monks au Royaume-Uni le 11 octobre au profit de la recherche sur l’ARSACS a eu un vif succ\u00e8s. Toutes nos f\u00e9licitations \u00e0 Maxine et \u00e0 son \u00e9quipe d’avoir organis\u00e9 cet \u00e9v\u00e9nement . Un gros merci \u00e0 tous les b\u00e9n\u00e9voles,…<\/p>\n<\/div><\/div><\/article>

\"The<\/span><\/a><\/div>

The “Charity Ball” – a great success!<\/a><\/h2>

Nov 13, 2025<\/span><\/p>

The first “Charity Ball” organized by Maxine Monks in the UK on October 11 to support ARSACS research had a great success. Congratulations to Maxine and her team for organizing the event. Thank you to all the volunteers, sponsors and donors for their generosity who…<\/p>\n<\/div><\/div><\/article>

\"A<\/span><\/a><\/div>

A school project to support ARSACS research<\/a><\/h2>

Nov 12, 2025<\/span><\/p>

Thank you to William Harvey and his entire team for their initiative as part of a year-end project at Arvida High School last May. This fundraiser consisted of selling hot dogs and treats. Their donation of $345 is greatly appreciated and will contribute to ARSACS…<\/p>\n<\/div><\/div><\/article>

\"Un<\/span><\/a><\/div>

Un projet de fin d’ann\u00e9e scolaire pour la recherche<\/a><\/h2>

Nov 12, 2025<\/span><\/p>

Merci \u00e0 William Harvey et toute son \u00e9quipe pour leur initiative dans le cadre d\u2019un projet de fin d\u2019ann\u00e9e \u00e0 la Polyvalente d’Arvida en mai dernier. Cette collecte de fonds consistait en la vente de hot-dogs et de friandises. \u00a0Leur don de 345 $ est grandement appr\u00e9ci\u00e9…<\/p>\n<\/div><\/div><\/article>

\"A<\/span><\/a><\/div>

A case of ARSACS detected in Uruguay<\/a><\/h2>

Nov 4, 2025<\/span><\/p>

ARSACS is around the world. The first clinical case, involving a 3-year-old girl, led to research funded by the Ataxia Charlevoix-Saguenay Foundation. A Radio Canada interview with neurologists from Quebec on the subject. (Interview available in French only).<\/p>\n<\/div><\/div><\/article>

\"Un<\/span><\/a><\/div>

Un cas d’ARSACS d\u00e9tect\u00e9 en Uruguay<\/a><\/h2>

Nov 4, 2025<\/span><\/p>

L’ARSACS est \u00e0 travers le monde. Le premier cas clinique d\u2019une fillette de 3 ans est \u00e0 l\u2019origine de travaux de recherche financ\u00e9s par la Fondation de l’Ataxie Charlevoix Saguenay. Entrevue de Radio Canada avec des neurologues du Qu\u00e9bec sur le sujet.<\/p>\n<\/div><\/div><\/article>

\"Invitation<\/span><\/a><\/div>

Invitation \u00e0 devenir un partenaire de Rare.QC<\/a><\/h2>

Oct 21, 2025<\/span><\/p>

Vous vivez avec une maladie rare, ou vous accompagnez une personne atteinte d\u2019une maladie rare? Vous voulez faire entendre votre voix et aider \u00e0 faire avancer la recherche? Devenez membre partenaire du r\u00e9seau de recherche de RARE.QC. En savoir plus.<\/p>\n<\/div><\/div><\/article>

\"Invitation<\/span><\/a><\/div>

Invitation to become a partner of RARE.QC<\/a><\/h2>

Oct 21, 2025<\/span><\/p>

Do you live with a rare disease, or are you supporting someone who does? Do you want tomake your voice heard and help advance research? Become a partner member of Rare Qc research network. Invitation<\/p>\n<\/div><\/div><\/article>

\"Two<\/span><\/a><\/div>

Two interesting articles related to ARSACS from China<\/a><\/h2>

Oct 17, 2025<\/span><\/p>

The first article “Genetic Analysis of three patients from two unrelated Chinese families with autosomal recessive spastic ataxia of Charlevoix- Saguenay” published in BMC Medical Genomics in 2025. Read here. The second article is a case report “Scalp acupuncture…<\/p>\n<\/div><\/div><\/article>

\"2<\/span><\/a><\/div>

2 articles int\u00e9ressants concernant l’ARSACS publi\u00e9s en Chine.<\/a><\/h2>

Oct 17, 2025<\/span><\/p>

Le premier article  \u201cGenetic Analysis of three patients from two unrelated Chinese families with autosomal recessive spastic ataxia of Charlevoix- Saguenay\u201d publi\u00e9 dans BMC Medical Genomics en 2025. Voir article. Le deuxi\u00e8me article est un cas report\u00e9…<\/p>\n<\/div><\/div><\/article>

\"Funded<\/span><\/a><\/div>

Funded ARSACS projects in 2025-2026<\/a><\/h2>

Oct 7, 2025<\/span><\/p>

The Ataxia Charlevoix Saguenay Foundation is pleased to announce the funding of 13 innovative ARSACS projects in 2025-2026 for an investment of $1.150M. A number of these projects have been made possible through a co-funding partnership with the Richardson Trust Fund….<\/p>\n<\/div><\/div><\/article>

\"Annonce<\/span><\/a><\/div>

Annonce des projets ARSACS en 2025-2026<\/a><\/h2>

Oct 7, 2025<\/span><\/p>

La Fondation Ataxie Charlevoix Saguenay est heureuse d’annoncer le financement de 13 projets ARSACS en 2025-2026 totalisant un investissement de 1.150 M$. Plusieurs de ces projets ont \u00e9t\u00e9 rendus possibles gr\u00e2ce \u00e0 un partenariat de cofinancement avec le Richardson…<\/p>\n<\/div><\/div><\/article>

\"\u201cComment<\/span><\/a><\/div>

\u201cComment les t\u00e9moignages des patients alimentent la recherche sur les ataxies \u201d\u00a0<\/a><\/h2>

Oct 7, 2025<\/span><\/p>

(article en version anglaise seulement) Un article tr\u00e8s int\u00e9ressant publi\u00e9 en septembre par le Oxford-Harrington Rare disease Centre avec Dre Esther Becker qui fait partie de l’\u00e9quie de recherche ARSACS et Sonia Gobeil, co-fondatrice de la Fondation de l’Ataxie…<\/p>\n<\/div><\/div><\/article>

\"“How<\/span><\/a><\/div>

“How Patient Stories Fuel Ataxia Research”\u00a0<\/a><\/h2>

Oct 7, 2025<\/span><\/p>

A very interesting article published in September by the Oxford-Harrington Rare Disease Centre featuring Dr. Esther Becker who is conducting ARSACS research and Sonia Gobeil co-founder of the Ataxia Charlevoix- Saguenay. “How Patient Stories Fuel Ataxia Research”<\/p>\n<\/div><\/div><\/article>

Genetic Analysis of three patients from two unrelated Chinese families with autosomal recessive spastic ataxia of Charlevoix- Saguenay<\/a><\/h2>

Oct 1, 2025<\/span><\/p>

Genetic Analysis of three patients from two unrelated Chinese families with autosomal recessive spastic ataxia of Charlevoix- Saguenay \u2013 . An article published in BMC Medical Genomics in 2025..<\/p>\n<\/div><\/div><\/article>

Scalp acupuncture combined with physiotherapy for ARSACS<\/a><\/h2>

Oct 1, 2025<\/span><\/p>

Scalp acupuncture combined with physiotherapy for ARSACS \u2013 . A case report published in China in the Helyion Journal in 2024..<\/p>\n<\/div><\/div><\/article>

\"Infolettre<\/span><\/a><\/div>

Infolettre #5 \u2013 \u00c9dition Automne 2025<\/a><\/h2>

Sep 29, 2025<\/span><\/p>

Nous sommes heureux de partager avec vous les plus r\u00e9centes nouvelles de la Fondation de l\u2019Ataxie Charlevoix-Saguenay. Dans cette \u00e9dition, vous trouverez un article scientifique r\u00e9cemment publi\u00e9 sur l\u2019ARSACS, des d\u00e9tails sur les projets de recherche financ\u00e9s par la…<\/p>\n<\/div><\/div><\/article>

\"Newsletter<\/span><\/a><\/div>

Newsletter #5 \u2013 Autumn 2025 Edition<\/a><\/h2>

Sep 29, 2025<\/span><\/p>

We are excited to share the latest updates from the Ataxia of Charlevoix-Saguenay Foundation. In this edition, you will find a newly published scientific article on ARSACS, details about the research projects funded by the Foundation for 2025\u20132026, and an invitation…<\/p>\n<\/div><\/div><\/article>

“Exploring the contributions of DCN alterations to cerebellar dysfunction inARSACS” – Dre Alanna Watt<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

In ARSACS, the cerebellum, critical for coordination and balance, is one of the most affected brain regions. Within the cerebellum, communication between Purkinje cells and the cerebellar nuclei, which helps integrate signals and execute coordinated movements, begins…<\/p>\n<\/div><\/div><\/article>

“Characterization of Clinically Relevant Compounds Modulating the ARSACS associated Phenoty\u0440\u0435” – Dr Mohan Babu<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare inherited disease that damages the nervous system and muscles, caused by faults in a protein called sacsin. There is currently no cure, and existing treatments only ease some symptoms. To…<\/p>\n<\/div><\/div><\/article>

“Scalable therapeutic testing in the ARSACS mouse” – Drs Justin Wolter & Huaxia Wang<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

Our project aims to accelerate drug discovery for ARSACS by using advanced single nucleus RNA sequencing (snRNAseq) to test 8 therapeutic candidates in the ARSACS mouse model (including ongoing studies led by Drs. Gentil\/Durham, and Drs. Lim\/Schmahmann). Unlike…<\/p>\n<\/div><\/div><\/article>

“Redefining ARSACS: Exploring TDP-43 Proteinopathy as a Novel Pathogenic Mechanism” – Dr Fran\u00e7ois Gros-Louis<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

Notre projet de recherche vise \u00e0 mieux comprendre l\u2019ARSACS. Gr\u00e2ce \u00e0 une analyse approfondie du cerveau d\u2019un patient d\u00e9c\u00e9d\u00e9 ayant g\u00e9n\u00e9reusement consenti au don d\u2019organes \u00e0 des fins de recherche, nous avons identifi\u00e9 des anomalies similaires \u00e0 celles observ\u00e9es dans…<\/p>\n<\/div><\/div><\/article>

“Developing conditional mouse models and new approaches to treating ARSACS\u201d – Dr Stefan Strack<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

The Sacs knock-out (KO) mouse is a faithful model of ARSACS, displaying ataxia, muscle weakness, cerebellar degeneration, and, as we have recently shown, learning and memory deficits. With this proposal, we seek to pharmacologically rescue motor- and cognitive…<\/p>\n<\/div><\/div><\/article>

\u201cTherapeutic Approaches for ARSACS\u201d- Dr Benoit Gentil et Dre Heather Durham<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

This research focuses on developing a potential gene therapy for ARSACS, a rare inherited neurological disease. Scientists created a smaller version of the faulty protein (called\u00a0minisacsin) that can fit into a viral vector for delivery to nerve cells. In mouse…<\/p>\n<\/div><\/div><\/article>

“Unveiling the Role of Microglia in ARSACS: A Multi-Model Approach IntegratingHuman Microglial and Zebrafish Models”- Dr Devid Damiani<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

As many other neurodegenerative diseases, ARSACS is also a matter of inflammation. Recent researches clarified that high levels of Sacsin protein are present in astrocytes and microglia, the cell populations of the brain that act like principal mediators of…<\/p>\n<\/div><\/div><\/article>

\u201cStructural Determination of Sacsin\u201d- Dr Walid Houry<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) was described in 1978 as a unique form of ataxia accompanied with motor speech anomalies, muscle wasting phenotypes, and peripheral nerve complications. Genetic studies have established that ARSACS is…<\/p>\n<\/div><\/div><\/article>

\u201cTargeting Cav2.1 to recover firing defects anddegeneration of Purkinje neurons in ARSACS\u201d – Dre Francesca Maltecca<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

A central theme in cerebellar ataxia is mutations in genes encoding calcium regulatory genes, highlighting the selective vulnerability of Purkinje neurons to alteration of calcium fluxes. We have recently demonstrated that the Voltage-Gated Calcium Channel (VGCC)…<\/p>\n<\/div><\/div><\/article>

“Targeting Scn4b as a therapy to rescue ataxia in a mouse model of ARSACS” – Dre R. Anne McKinney<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

As cerebellar dysfunction is thought to underlie ARSACS pathology, work from the\u00a0McKinney lab focus on identifying novel disease-causing mechanisms in a mouse model of ARSACS, as well as implementing new therapeutic approaches to ameliorate cerebellar function and…<\/p>\n<\/div><\/div><\/article>

“Advanced MRI studies to achieve microstructural insight and identifyimaging biomarkers in ARSACS ” – Dre Roberta La Piana<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

The involvement of the corticospinal tracts (CST) and cerebellum are the disease hallmarks of ARSACS. Previous radiological studies documented the presence of specific findings which were described as\u00a0linear hypointensities in T2-weighted images at the level of the…<\/p>\n<\/div><\/div><\/article>

“Exploring the Role of Sacsin on Blood-Brain Barrier Cell Structure, Behavior and Function” – Dr Federico Herrera<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

Loss of sacsin affect neurons in the cerebellum, but the role of other, non-neuronal brain cells in ARSACS has been less studied. The team discovered high amounts of sacsin in the cells that form the blood-brain barrier\u2014a protective layer that keeps harmful substances…<\/p>\n<\/div><\/div><\/article>

” A transcriptomic approach to drug discovery against ARSACS ” – Dr Nicolas Dupr\u00e9<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

Ce projet de recherche vise \u00e0 d\u00e9couvrir de nouvelles cibles th\u00e9rapeutiques et des m\u00e9dicaments potentiels pour l’ARSACS en combinant des \u00e9chantillons sanguins de\u00a0 patients avec la technologie des iPSC (cellules souches pluripotentes induites) et l’intelligence…<\/p>\n<\/div><\/div><\/article>

“Targeting Scn4b as a therapy to rescue ataxia in a mouse model of ARSACS\u201d – Dr. R. Anne McKinney<\/a><\/h2>

Sep 25, 2025<\/span><\/p>

As cerebellar dysfunction is thought to underlie ARSACS pathology, work from the McKinney lab focus on identifying novel disease-causing mechanisms in a mouse model of ARSACS, as well as implementing new therapeutic approaches to ameliorate cerebellar function and…<\/p>\n<\/div><\/div><\/article>

“Redefining ARSACS: Exploring TDP-43 Proteinopathy as a Novel Pathogenic Mechanism ” – Dr. Fran\u00e7ois Gros-Louis<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

Our research project aims to improve our understanding of ARSACS. Through an in-depth analysis of the brain of a deceased patient who generously consented to organ donation for research purposes, we identified abnormalities like those observed in…<\/p>\n<\/div><\/div><\/article>

“Scalable therapeutic testing in the ARSACS mouse” – Drs. Justin Wolter & Huaxia Wang<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

Our project aims to accelerate drug discovery for ARSACS by using advanced single nucleus RNA sequencing (snRNAseq) to test 8 therapeutic candidates in the ARSACS mouse model (including ongoing studies led by Drs. Gentil\/Durham, and Drs. Lim\/Schmahmann). Unlike…<\/p>\n<\/div><\/div><\/article>

“Therapeutic Approaches for ARSACS”- Dr. Benoit Gentil and Dr. Heather Durham<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

This research focuses on developing a potential gene therapy for ARSACS, a rare inherited neurological disease. Scientists created a smaller version of the faulty protein (called\u00a0minisacsin) that can fit into a viral vector for delivery to nerve cells. In mouse…<\/p>\n<\/div><\/div><\/article>

\u201cStructural Determination of Sacsin\u201d – Dr. Walid Houry<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) was described in 1978 as a unique form of ataxia accompanied with motor speech anomalies, muscle wasting phenotypes, and peripheral nerve complications. Genetic studies have established that ARSACS is…<\/p>\n<\/div><\/div><\/article>

“Developing conditional mouse models and new approaches to treating ARSACS” – Dr. Stefan Strack<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

The Sacs knock-out (KO) mouse is a faithful model of ARSACS, displaying ataxia, muscle weakness, cerebellar degeneration, and, as we have recently shown, learning and memory deficits. With this proposal, we seek to pharmacologically rescue motor- and cognitive…<\/p>\n<\/div><\/div><\/article>

\u201c Targeting Cav2.1 to recover firing defects and degeneration of Purkinje neurons in ARSACS \u201d – Dr. Francesca Maltecca<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

A central theme in cerebellar ataxia is mutations in genes encoding calcium regulatory genes, highlighting the selective vulnerability of Purkinje neurons to alteration of calcium fluxes. We have recently demonstrated that the Voltage-Gated Calcium Channel (VGCC)…<\/p>\n<\/div><\/div><\/article>

“Characterization of Clinically Relevant Compounds Modulating the ARSACS associated Phenoty\u0440\u0435” – Dr. Mohan Babu<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a rare inherited disease that damages the nervous system and muscles, caused by faults in a protein called sacsin. There is currently no cure, and existing treatments only ease some symptoms. To…<\/p>\n<\/div><\/div><\/article>

“Exploring the contributions of DCN alterations to cerebellar dysfunction in ARSACS” – Dr. Alanna Watt<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

In ARSACS, the cerebellum, critical for coordination and balance, is one of the most affected brain regions. Within the cerebellum, communication between Purkinje cells and the cerebellar nuclei, which helps integrate signals and execute coordinated movements, begins…<\/p>\n<\/div><\/div><\/article>

“Unveiling the Role of Microglia in ARSACS: A Multi-Model Approach Integrating Human Microglial and Zebrafish Models” – Dr. Devid Damiani<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

As many other neurodegenerative diseases, ARSACS is also a matter of inflammation. Recent researches clarified that high levels of Sacsin protein are present in astrocytes and microglia, the cell populations of the brain that act like principal mediators of…<\/p>\n<\/div><\/div><\/article>

“Advanced MRI studies to achieve microstructural insight and identify imaging biomarkers in ARSACS ” – Dr. Roberta LaPiana<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

The involvement of the corticospinal tracts (CST) and cerebellum are the disease hallmarks of ARSACS. Previous radiological studies documented the presence of specific findings which were described as linear hypointensities in T2-weighted images at the level of…<\/p>\n<\/div><\/div><\/article>

“Exploring the Role of Sacsin on Blood-Brain Barrier Cell Structure, Behavior and Function” – Dr. Federico Herrera<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

Loss of sacsin affect neurons in the cerebellum, but the role of other, non-neuronal brain cells in ARSACS has been less studied. The team discovered high amounts of sacsin in the cells that form the blood-brain barrier\u2014a protective layer that keeps harmful substances…<\/p>\n<\/div><\/div><\/article>

“A transcriptomic approach to drug discovery against ARSACS ” – Dr. Nicolas Dupr\u00e9<\/a><\/h2>

Sep 24, 2025<\/span><\/p>

This project aims to discover new therapeutic targets and potential drugs for ARSACS by combining blood samples from patients with advanced iPSC (induced pluripotent stem cell) technology and artificial intelligence (AI). The team will analyze gene expression patterns…<\/p>\n<\/div><\/div><\/article>

Biophysical and functional study of Sacsin Trojan fragments as a protein complementation and phenotypic rescue strategy for ARSACS \u2013 by Dr. Javier Santos, Buenos Aires University, Argentina<\/a><\/h2>

Sep 8, 2025<\/span><\/p>

Biophysical and functional study of Sacsin Trojan fragments as a protein complementation and phenotypic rescue strategy for ARSACS \u2013 by Dr. Javier Santos, Buenos Aires University, Argentina . This project was funded by the ARSACS Foundation in 2024\u20132025<\/p>\n<\/div><\/div><\/article>

\"Rapport<\/span><\/a><\/div>

Rapport de projet du Dr Javier Santos<\/a><\/h2>

Sep 4, 2025<\/span><\/p>

Nous vous pr\u00e9sentons le rapport du projet de recherche du Dr Javier Santos, intitul\u00e9 \u00ab Biophysical and functional study of Sacsin Trojan fragments as a protein complementation and phenotypic rescue strategy for ARSACS \u00bb. Ce projet a \u00e9t\u00e9 financ\u00e9 par la Fondation pour…<\/p>\n<\/div><\/div><\/article>

\"Dr.<\/span><\/a><\/div>

Dr. Javier Santos\u2019 Project Report<\/a><\/h2>

Sep 3, 2025<\/span><\/p>

We are pleased to present Dr. Javier Santos\u2019 research project report, entitled \u201cBiophysical and functional study of Sacsin Trojan fragments as a protein complementation and phenotypic rescue strategy for ARSACS.\u201d . This project was funded by the ARSACS Foundation for…<\/p>\n<\/div><\/div><\/article>

\"Sondage<\/span><\/a><\/div>

Sondage international sur la th\u00e9rapie g\u00e9nique pour les ataxies g\u00e9n\u00e9tiques<\/a><\/h2>

Ao\u00fbt 26, 2025<\/span><\/p>

Les personnes vivant avec l’ARSACS (ou parent\/tuteur) sont invit\u00e9es \u00e0 r\u00e9pondre \u00e0 un sondage en ligne visant \u00e0 recueillir leurs opinions sur la th\u00e9rapie g\u00e9nique. \ud83d\udd39 Objectif : orienter la conception des futurs projets de recherche et essais cliniques\u23f3 Dur\u00e9e : ~30…<\/p>\n<\/div><\/div><\/article>

\"International<\/span><\/a><\/div>

International survey on gene therapy for genetic ataxias<\/a><\/h2>

Ao\u00fbt 26, 2025<\/span><\/p>

People living with a ARSACS (or parent\/guardian) are invited to take part in an online survey about gene therapy. \ud83d\udd39 Purpose: to gather opinions that will help shape future research projects and clinical trial design\u23f3 Duration: ~30 minutes \u2013 anonymous\ud83d\uddd3\ufe0f Deadline: End…<\/p>\n<\/div><\/div><\/article>

Webinaire en direct<\/a><\/h2>

Ao\u00fbt 19, 2025<\/span><\/p>

Pour plus de d\u00e9tails, cliquez ici<\/p>\n<\/div><\/div><\/article>

\"LIVE<\/span><\/a><\/div>

LIVE Webinar<\/a><\/h2>

Ao\u00fbt 19, 2025<\/span><\/p>

For more details click here  <\/p>\n<\/div><\/div><\/article>

\"Rapport<\/span><\/a><\/div>

Rapport du projet de recherche de la Dre Martina Crispo<\/a><\/h2>

Ao\u00fbt 6, 2025<\/span><\/p>

Nous vous pr\u00e9sentons le rapport du projet de recherche de Dre Martina Crispo (Institut Pasteur de Montevideo, Uruguay), intitul\u00e9 \u00ab Avatar mouse model of a new genetic variant of ARSACS detected in Uruguay \u00bb. Ce projet a \u00e9t\u00e9 financ\u00e9 par la Fondation pour l\u2019ann\u00e9e…<\/p>\n<\/div><\/div><\/article>

\"Dr.<\/span><\/a><\/div>

Dr. Martina Crispo’s Research Report<\/a><\/h2>

Ao\u00fbt 6, 2025<\/span><\/p>

We are pleased to present Dr. Marina Crispo\u2019s research project report (Institute Pasteur de Montevideo, Uruguay), entitled “Avatar mouse model of a new genetic variant of ARSACS detected in Uruguay”. . This project was funded by the ARSACS Foundation for the 2024\u20132025…<\/p>\n<\/div><\/div><\/article>

Identification of a novel SACS gene mutation leading to spastic ataxia Charlevoix-Saguenay type: a case report<\/a><\/h2>

Ao\u00fbt 1, 2025<\/span><\/p>

Identification of a novel SACS gene mutation leading to spastic ataxia Charlevoix-Saguenay type: a case report \u2013 . Research conducted in Uruguay and published in the Journal of Medical Case Reports in August 2025..<\/p>\n<\/div><\/div><\/article>

\"Publication<\/span><\/a><\/div>

Publication r\u00e9cente sur l\u2019ARSACS<\/a><\/h2>

Juil 31, 2025<\/span><\/p>

Nous vous partageons l’article scientifique intitul\u00e9 \u00ab Sacsin deletion decreases cell viscoelasticity and motility in a glial cell model of autosomal recessive spastic ataxia of Charlevoix Saguenay \u00bb, issu des travaux du Dr Federico Herrera et collaborateurs, publi\u00e9…<\/p>\n<\/div><\/div><\/article>

\"Recent<\/span><\/a><\/div>

Recent Publication on ARSACS<\/a><\/h2>

Juil 31, 2025<\/span><\/p>

We are pleased to share the scientific article entitled ” Sacsin deletion decreases cell viscoelasticity and motility in a glial cell model of autosomal recessive spastic ataxia of Charlevoix Saguenay”, based on the work of Dr. Federico Herrera and colleagues,…<\/p>\n<\/div><\/div><\/article>

\"Recherche<\/span><\/a><\/div>

Recherche sur l\u2019ARSACS et l\u2019ARN<\/a><\/h2>

Juil 22, 2025<\/span><\/p>

Dr Benoit Gentil (McGill) a r\u00e9cemment obtenu un financement important pour un projet qui vise \u00e0 d\u00e9velopper une approche th\u00e9rapeutique pour l\u2019ARSACS bas\u00e9e sur l\u2019ARN en utilisant une technologie de nanoparticules. Ce projet est men\u00e9 en collaboration avec QurCan…<\/p>\n<\/div><\/div><\/article>

\"ARSACS<\/span><\/a><\/div>

ARSACS and RNA Research<\/a><\/h2>

Juil 22, 2025<\/span><\/p>

Dr. Benoit Gentil (McGill) was recently awarded significant funding for a project aiming to develop an RNA-based therapeutic approach for ARSACS using nanoparticle technology. This project is being carried out in collaboration with QurCan Therapeutics and Genome…<\/p>\n<\/div><\/div><\/article>

\"Infolettre<\/span><\/a><\/div>

Infolettre #4 \u2013 \u00c9dition \u00c9t\u00e9 2025<\/a><\/h2>

Juil 10, 2025<\/span><\/p>

Dans cette \u00e9dition, d\u00e9couvrez les derni\u00e8res nouvelles de la Fondation, dont un article scientifique r\u00e9cemment publi\u00e9 sur l\u2019ARSACS, un aper\u00e7u du prochain Diner des Producteurs 2025, ainsi que des informations sur notre participation \u00e0 venir au WODC Europe \u00e0 Amsterdam….<\/p>\n<\/div><\/div><\/article>

\"Newsletter<\/span><\/a><\/div>

Newsletter #4 \u2013 Summer 2025 Edition<\/a><\/h2>

Juil 10, 2025<\/span><\/p>

In this issue, discover the latest updates from the Foundation, including a newly published scientific article on ARSACS, a preview of the upcoming 2025 Diner des Producteurs, and details about our upcoming participation in the WODC Europe in Amsterdam. Read it now<\/p>\n<\/div><\/div><\/article>

Avatar mouse model of a new genetic variant of ARSACS detected in Uruguay \u2013 by Dr. Martina Crispo, Institut Pasteur de Montevideo, Uruguay<\/a><\/h2>

Juil 8, 2025<\/span><\/p>

Avatar mouse model of a new genetic variant of ARSACS detected in Uruguay \u2013 by Dr. Martina Crispo, Institut Pasteur de Montevideo, Uruguay . This project was funded by the ARSACS Foundation in 2024\u20132025<\/p>\n<\/div><\/div><\/article>

\"Nouveau<\/span><\/a><\/div>

Nouveau groupe de soutien ARSACS<\/a><\/h2>

Juil 7, 2025<\/span><\/p>

Natalie et Rachael Seals, elles-m\u00eames touch\u00e9es par l\u2019ARSACS, lancent un groupe de soutien en ligne. Prochaines rencontres sur Zoom : Samedi 2 ao\u00fbt \u00e0 10h Samedi 4 octobre \u00e0 10h Inscription obligatoire pour participer. Pour vous inscrire ou en savoir plus :…<\/p>\n<\/div><\/div><\/article>

\"New<\/span><\/a><\/div>

New ARSACS Support Group<\/a><\/h2>

Juil 7, 2025<\/span><\/p>

Natalie and Rachael Seals, who are personally affected by ARSACS, are starting an online support group. Upcoming Zoom meetings: Saturday 2 August at 10am Saturday 4 October at 10am Registration required to join. For details or to sign up: volunteering@ataxia.org.uk<\/p>\n<\/div><\/div><\/article>

\"PARTICIPEZ<\/span><\/a><\/div>

PARTICIPEZ \u00c0 UNE \u00c9TUDE EN LIGNE<\/a><\/h2>

Juil 2, 2025<\/span><\/p>

Le Schmahmann Laboratory (Massachusetts General Hospital Ataxia Center, Boston) recrute des adultes atteints de maladies c\u00e9r\u00e9belleuses pour valider un nouvel outil d\u2019\u00e9valuation des aspects \u00e9motionnels du syndrome cognitif et affectif c\u00e9r\u00e9belleux (CCAS). Qui peut…<\/p>\n<\/div><\/div><\/article>

\"JOIN<\/span><\/a><\/div>

JOIN AN ONLINE STUDY<\/a><\/h2>

Juil 2, 2025<\/span><\/p>

The Schmahmann Laboratory (Massachusetts General Hospital Ataxia Center, Boston) is conducting a study to validate a new tool for assessing emotional aspects related to the Cerebellar Cognitive and Affective Syndrome (CCAS). Who can participate?\ud83d\udc49 English-speaking…<\/p>\n<\/div><\/div><\/article>

Long-term benefits of TUDCA supplement in ARSACS zebrafish model<\/a><\/h2>

Juil 1, 2025<\/span><\/p>

Long-term benefits of TUDCA supplement in ARSACS zebrafish model \u2013 Dr. Valentina Naef. Research by Dr. Valentina Naef and her team, published in Scientific Reports in July 2025..<\/p>\n<\/div><\/div><\/article>

Sacsin deletion decreases cell viscoelasticity and motility in a glial cell model of autosomal recessive spastic ataxia of Charlevoix Saguenay<\/a><\/h2>

Juil 1, 2025<\/span><\/p>

Sacsin deletion decreases cell viscoelasticity and motility in a glial cell model of autosomal recessive spastic ataxia of Charlevoix Saguenay \u2013 Dr. Federico Herrera. Based on the work of Dr. Federico Herrera and colleagues, published in July 2025 in Archives of…<\/p>\n<\/div><\/div><\/article>

La Fondation ARSACS pr\u00e9sentera au WODC Europe 2025<\/a><\/h2>

Juin 18, 2025<\/span><\/p>

Nous sommes fiers d\u2019annoncer notre participation au World Orphan Drug Congress (WODC) Europe, qui se tiendra en octobre prochain \u00e0 Amsterdam. Un kiosque sera sur place nous permettant d’\u00e9changer avec les participants et faire conna\u00eetre notre mission aupr\u00e8s des acteurs…<\/p>\n<\/div><\/div><\/article>

\"The<\/span><\/a><\/div>

The ARSACS Foundation to Present at WODC Europe 2025<\/a><\/h2>

Juin 18, 2025<\/span><\/p>

We are proud to announce our participation to the World Orphan Drug Congress (WODC) Europe, which will be held this October in Amsterdam. A booth will be displayed to engage with attendees and raise awareness about our mission among international stakeholders in the…<\/p>\n<\/div><\/div><\/article>

\"Revue<\/span><\/a><\/div>

Revue sur les ataxies r\u00e9cessives<\/a><\/h2>

Juin 5, 2025<\/span><\/p>

Nous sommes heureux de partager un article publi\u00e9 dans le journal Annals of Neurology, portant sur les ataxies c\u00e9r\u00e9belleuses autosomiques r\u00e9cessives, incluant l\u2019ARSACS. Lire l\u2019article ici<\/p>\n<\/div><\/div><\/article>

\"Review<\/span><\/a><\/div>

Review on Recessive Ataxias<\/a><\/h2>

Juin 5, 2025<\/span><\/p>

We are pleased to share a review published in the journal Annals of Neurology on autosomal recessive cerebellar ataxias, including ARSACS. Read article here<\/p>\n<\/div><\/div><\/article>

\"Th\u00e8se<\/span><\/a><\/div>

Th\u00e8se et publication issues d\u2019un projet financ\u00e9<\/a><\/h2>

Juin 3, 2025<\/span><\/p>

Un article issu d\u2019un projet financ\u00e9 par la Fondation en 2022\u20132023 vient d\u2019\u00eatre publi\u00e9. Cette recherche sur des mod\u00e8les cellulaires de l\u2019ARSACS a aussi permis \u00e0 Dre Fernanda Murtinheira de soutenir avec succ\u00e8s sa th\u00e8se de doctorat. Bravo aux Drs Herrera et Murtinheira…<\/p>\n<\/div><\/div><\/article>

\"PhD<\/span><\/a><\/div>

PhD and Publication from a Funded Project<\/a><\/h2>

Juin 3, 2025<\/span><\/p>

A research article from a project funded by the Foundation in 2022\u20132023 has just been published. This study on cellular models of ARSACS also led to Dr. Fernanda Murtinheira successfully defending her PhD. Congrats to Drs. Fernanda and Federico Herrera for this…<\/p>\n<\/div><\/div><\/article>

\"Nouvelle<\/span><\/a><\/div>

Nouvelle publication scientifique sur l\u2019ARSACS<\/a><\/h2>

Mai 28, 2025<\/span><\/p>

D\u00e9couvrez cette r\u00e9cente publication scientifique sur l\u2019ARSACS.Les travaux de recherche ont \u00e9t\u00e9 financ\u00e9s par Associazione ARSACS ODV \u2013 Italy, une fondation mise sur pied par l\u2019un des membres de notre conseil d\u2019administration, Dr Paolo Arrigoni. Lire l\u2019article…<\/p>\n<\/div><\/div><\/article>

\"New<\/span><\/a><\/div>

New scientific publication on ARSACS<\/a><\/h2>

Mai 28, 2025<\/span><\/p>

Read about this recent scientific publication on ARSACS.The research featured in this article was funded by Associazione ARSACS ODV \u2013 Italy, a foundation established by one of the members of our Board of Directors, Dr. Paolo Arrigoni. Read the article<\/p>\n<\/div><\/div><\/article>

\"Diner<\/span><\/a><\/div>

Diner des Producteurs 2025<\/a><\/h2>

Mai 12, 2025<\/span><\/p>

Reservation \/ Sponsorship \/ Donation Form<\/p>\n<\/div><\/div><\/article>

Diner des Producteurs 2025<\/a><\/h2>

Mai 12, 2025<\/span><\/p>

Formulaire de R\u00e9servation \/ Commandite \/Don<\/p>\n<\/div><\/div><\/article>

Foundation-Funded Project Featured at ASGCT – May 2025<\/a><\/h2>

Mai 12, 2025<\/span><\/p>

A research project led by Dr. Benoit Gentil and funded by the Foundation will be presented at the American Society of Gene and Cell Therapy (ASGCT) annual meeting, a key event in the field of gene and cell therapy. The presentation video titled \u201cAtaxia of…<\/p>\n<\/div><\/div><\/article>

Sonia Gobeil Interview with CheckRare – April 2025<\/a><\/h2>

Mai 12, 2025<\/span><\/p>

Last April, Sonia Gobeil was interviewed by CheckRare during the World Orphan Drug Congress (WODC). This is a valuable opportunity to raise awareness for ARSACS (Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay) and to highlight the importance of ongoing…<\/p>\n<\/div><\/div><\/article><\/div><\/div><\/div>\n<\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

Lisez le r\u00e9cent rapport de Stefan Strack sur l’ARSACS, notamment ses travaux r\u00e9ussis sur l’administration du g\u00e8ne Sacsin humain complet en th\u00e9rapie g\u00e9nique. Lire l’article (disponible en anglais seulement).<\/p>","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-13366","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/pages\/13366","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/comments?post=13366"}],"version-history":[{"count":15,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/pages\/13366\/revisions"}],"predecessor-version":[{"id":25928,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/pages\/13366\/revisions\/25928"}],"wp:attachment":[{"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/media?parent=13366"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}