{"id":22621,"date":"2025-09-24T12:37:22","date_gmt":"2025-09-24T16:37:22","guid":{"rendered":"https:\/\/www.arsacs.com\/?p=22621"},"modified":"2026-03-16T18:18:12","modified_gmt":"2026-03-16T22:18:12","slug":"redefining-arsacs-exploring-tdp-43-proteinopathy-as-a-novelpathogenic-mechanism-by-dr-francois-gros-louis","status":"publish","type":"post","link":"https:\/\/2026.arsacs.com\/fr\/redefining-arsacs-exploring-tdp-43-proteinopathy-as-a-novelpathogenic-mechanism-by-dr-francois-gros-louis\/","title":{"rendered":"“Redefining ARSACS: Exploring TDP-43 Proteinopathy as a Novel Pathogenic Mechanism ” – Dr. Fran\u00e7ois Gros-Louis"},"content":{"rendered":"

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Our research project aims to improve our understanding of ARSACS. Through an in-depth analysis of the brain of a deceased patient who generously consented to organ donation for research purposes, we identified abnormalities like those observed in other diseases such as amyotrophic lateral sclerosis (ALS) and other brain disorders. These findings suggest that certain biological causes may be shared among these disorders. In the long term, this discovery paves the way for new avenues to develop targeted treatments for ARSACS.<\/p>\n\n\n\n

Grant: $100,000<\/p>\n\n\n\n

Duration: one year<\/p>\n\n\n\n

<\/p>\n\n\n\n

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Dr Fran\u00e7ois Gros-Louis
Centre de recherche du CHU de Qu\u00e9bec - LOEX
H\u00f4pital de l'Enfant-J\u00e9sus (Bureau R-211)
1401 18e rue Qu\u00e9bec, QC
G1J 1Z4<\/p>\n\n\n\n

Contact : francois.gros-louis@fmed.ulaval.ca<\/a><\/p>\n<\/div><\/div>\n<\/div>\n\n\n\n

<\/p>","protected":false},"excerpt":{"rendered":"

Our research project aims to improve our understanding of ARSACS. Through an in-depth analysis of the brain of a deceased patient who generously consented to organ donation for research purposes, we identified abnormalities like those observed in other diseases such as amyotrophic lateral sclerosis (ALS) and other brain disorders. These findings suggest that certain biological causes may be shared […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[],"class_list":["post-22621","post","type-post","status-publish","format-standard","hentry","category-current"],"_links":{"self":[{"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/22621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/comments?post=22621"}],"version-history":[{"count":12,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/22621\/revisions"}],"predecessor-version":[{"id":25128,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/posts\/22621\/revisions\/25128"}],"wp:attachment":[{"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/media?parent=22621"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/categories?post=22621"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/2026.arsacs.com\/fr\/wp-json\/wp\/v2\/tags?post=22621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}